The University of Arkansas for Medical Sciences (UAMS) South Central Regional Campus in Pine Bluff, Arkansas, stands as a pivotal part of the UAMS system since its inception in 1972. Serving as a regional teaching center, the campus is dedicated to patient care and the education of health professionals in a medically underserved area. One of its key offerings is the renowned Family Medicine Residency program, designed to provide residents with hands-on medical experience. Medical students from the main UAMS campus in Little Rock also benefit from rotations here, enhancing their practical exposure. With the unique resource of the Julie Dobbins/Melville Library, open for public health information research, and its location just 44 miles from Little Rock, the campus supports a population of around 43,000.

Additionally, UAMS Pine Bluff emphasizes health career recruitment to confront regional shortages of healthcare professionals. This vibrant campus is nestled in a city that merges historical charm with contemporary amenities, boasting attractions such as the Pine Bluff Convention Center, the Arts and Science Center, and America's only Band Museum. As part of the community integration efforts, UAMS offers housing assistance and local resource information to its students, further embedding them into Pine Bluff's culturally rich and engaging environment.