Trinity School of Nursing, situated in Steubenville, Ohio, offers a distinctive two-year diploma program in Registered Nursing (RN) education. Founded in 1912, this private, not-for-profit institution initially started as the Ohio Valley Hospital School of Nursing and has since evolved significantly. With an affiliation to St. John Medical Center since 1996, it is now known as Trinity Health System School of Nursing. The school prides itself on a 100% acceptance rate and outstanding NCLEX-RN pass rates, often surpassing both state and national averages, with the Class of 2022 achieving a remarkable perfect pass rate.

The curriculum at Trinity School of Nursing is designed to provide a holistic approach, balancing theoretical coursework with extensive hands-on clinical experience at Trinity Health System's facilities. Students benefit from the school's accreditation by the Accreditation Commission for Education in Nursing (ACEN) and approval by the Ohio Board of Nursing. A notable feature of the program is its optional scholarship, which covers tuition and fees in exchange for a full-time RN position at Trinity Health System, fostering seamless transition into professional roles. Relocated to the Eastern Gateway Community College campus in 2017, the school now boasts modern facilities, enhancing both learning and clinical training environments. This strategic location further strengthens its mission to prepare nurses for diverse healthcare settings, imbued with the values of Trinity Health System.