UCI Health's Irvine campus is a pioneering force in healthcare education and innovation, strategically located in Orange County. As part of the university's broader network, this campus is not only a medical facility but also a dynamic educational hub. The campus hosts numerous centers, including the UCI School of Medicine, which plays a vital role in nurturing the next generation of healthcare professionals. It emphasizes an integrated approach to education and practice, ensuring that students are immersed in both cutting-edge research and state-of-the-art clinical experiences.

The school is instrumental in advancing personalized medicine through its UCI Institute for Precision Health. With the integration of AI, machine learning, and genomics, students and faculty alike engage in groundbreaking work that positions the institute as a leader in personalized healthcare solutions. Furthermore, the campus's focus on sustainability sets it apart as the first all-electric, zero-emission medical center in the nation, offering future medical practitioners a unique perspective on environmentally conscious healthcare practices. Through this robust infrastructure, UCI Health’s Irvine campus is dedicated to its mission of "Discover. Teach. Heal," aligning educational excellence with transformative patient care.