South College's Pittsburgh campus is nestled in the vibrant community of Cranberry Township, Pennsylvania, at 3000 Westinghouse Drive, Suite 200. This modern facility, opened in 2023 after extensive renovations, spans over 23,327 square feet. It offers an advanced educational environment with state-of-the-art classrooms and specialized laboratories, including those for radiography, surgical technology, and nursing. The campus focuses primarily on healthcare professions, providing a range of associate's and bachelor's degree programs such as Diagnostic Medical Sonography, Health Science (Pre-Nursing), Radiography, and a Bachelor of Science in Nursing, along with certificate programs in Licensed Practical Nursing and Medical Assisting.

As part of the broader network of South College that originated in Knoxville, Tennessee, in 1882, the Pittsburgh campus continues the legacy of offering over 100 programs and concentrations. It emphasizes a practical and focused approach to education, aiming to develop students' critical thinking and real-world application skills. Situated conveniently with ample parking, the campus also ensures access to nearby amenities like restaurants and shopping. The college is regionally accredited and committed to serving the community by fostering partnerships and providing extensive support services, including financial aid and student services. Campus president Anne Petrella emphasizes their dedication to providing excellent education and resources to meet the needs of the local community.