Pacific College of Health and Science's San Diego campus, situated in the bustling Mission Valley district, offers a comprehensive educational experience dedicated to integrative and holistic health. Unlike traditional institutions, it provides a variety of programs such as acupuncture, massage therapy, and holistic nursing, spanning from associate's to doctoral degrees. The campus features state-of-the-art facilities that include a large professional acupuncture clinic with 30 treatment beds and an herbal dispensary, designed to offer practical, hands-on learning. This commitment to real-world application is bolstered by an open admissions policy, allowing access to diverse learners.

The school emphasizes a multidimensional approach to healthcare, incorporating traditional and contemporary practices. Its programs aim to equip students for careers in various holistic healthcare areas, and it also offers continuing education and online programs for wider accessibility. Popular majors such as Foods, Nutrition, and Wellness Studies, and Massage Therapy and Bodywork signify its unique curriculum focus. A supportive alumni network and abundant clinic opportunities further enhance the educational journey. While specific aspects of campus life like housing and sports are limited, the college's convenient location offers easy access to amenities and recreational activities, enriching the student experience.