Madonna University's Southfield campus offers its innovative Accelerated Bachelor of Science in Nursing (ABSN) program, explicitly designed for students with prior non-nursing college credits or an undergraduate degree. This 16-month program combines online courses with practical in-person skills and simulation labs, concluding with clinical rotations at renowned facilities like Henry Ford Health. Grounded in Catholic and Franciscan values, the curriculum promotes a holistic approach to preparing students as practice-ready registered nurses. The Southfield location provides easy access to the robust resources of Madonna University's larger system while emphasizing personalized instruction and student success.

As part of the esteemed College of Nursing and Health, which holds over 50 years of excellence in nursing education, this campus is dedicated to fostering an environment conducive to academic and professional growth. Students have access to the comprehensive resources and support services offered by the main campus in Livonia, Michigan. Additionally, Madonna University is committed to affordability, offering numerous scholarships and grants to its diverse student body. This support is supplemented by a dedicated admissions team, guiding students through every step of the application and program process, ensuring a seamless educational journey.