Gadsden State Community College's Anniston campus, also known as the Ayers Campus, is a cornerstone of learning situated in Anniston, Alabama. Established in 1966, this 25-acre campus is part of a multi-campus community college system dedicated to providing accessible and affordable education. It offers a comprehensive range of associate degrees and certificate programs, tailored to both transfer and career-focused pathways, making it a favorite choice for students from the local region, including those commuting from Birmingham. The campus upholds a commendable student-to-faculty ratio of 18:1, ensuring personalized attention and a supportive educational environment.

Ayers Campus is distinguished by its historical roots as a former technical college, highlighting its longstanding commitment to technical training and educational advancement in Alabama. The open admissions policy and availability of remedial services reflect the college's dedication to inclusivity and student success. With a variety of academic and vocational programs, Gadsden State Anniston prepares its diverse student body for myriad career paths or continued study at four-year institutions. Part of the Alabama Community College System and accredited by the Southern Association of Colleges and Schools, the Ayers Campus stands as an essential component of Alabama's broader educational landscape, echoing the college's mission to expand higher education opportunities throughout the region.