DeVry University's Orlando campus, situated just ten miles from the vibrant downtown Orlando, is committed to delivering a blend of on-campus and flexible online learning experiences. The campus offers a comprehensive range of undergraduate and graduate programs across diverse fields such as business, healthcare, and technology. Notably, the undergraduate programs include accounting, business management, health administration, and software development, while the graduate offerings feature MBAs and master's degrees in project management and information technology.

Students at the Orlando campus enjoy access to valuable resources, including a virtual research library, comfortable classrooms, and extensive online learning tools paired with robust support services. The campus fosters a supportive academic environment with dedicated student support specialists, financial aid guidance, and career development assistance. Despite being primarily a commuter campus, it encourages community through various student organizations and professional associations. Additionally, the Orlando campus is recognized for its technology-centered academic environment and is accredited by The Higher Learning Commission (HLC), with the Keller Graduate School of Management included in this accreditation. The school emphasizes career-focused education, and its inclusive student body is notably diverse, enhancing the overall educational experience.